PUBLIC HEALTH PHARMACY

PHARMACOGNOSY AND PHYTOCHEMISTRY II BP504T

UNIT -01

Metabolic pathways in higher plants and their determination
Brief study of basic metabolic pathways and formation of different secondary metabolites through these pathways- Shikimic acid pathway, Acetate pathways and Amino acid pathway. Study of utilization of radioactive isotopes in the investigation of Biogenetic studies.

UNIT -02

General introduction, composition, chemistry & chemical classes, bio -sources, therapeutic uses and commercial applications of following secondary metabolites:
Alkaloids: Vinca, Rauwolfia, Belladonna, Opium.
Phenylpropanoids and Flavonoids: Lignans, Tea, Ruta.
Steroids, Cardiac Glycosides & Triterpenoids: Liquorice, Dioscorea, Digitalis.
Volatile oils: Mentha, Clove, Cinnamon, Fennel, Coriander.
Tannins: Catechu, Pterocarpus.
Resins: Benzoin, Guggul, Ginger, Asafoetida, Myrrh, Colophony.
Glycosides: Senna, Aloes, Bitter Almond.
Iridoids, Other terpenoids & Naphthaquinones: Gentian, Artemisia, Taxus, carotenoids

UNIT -03

  • Isolation, Identification and Analysis of Phytoconstituents.
    Terpenoids: Menthol, Citral, Artemisin.
    Glycosides: Glycyrhetinic acid & Rutin.
    Alkaloids: Atropine, Quinine, Reserpine, Caffeine
    Resins: Podophyllotoxin, Curcumin.

UNIT -04

  • Industrial production, estimation and utilization of the following phytoconstituents: Forskolin, Sennoside, Artemisinin, Diosgenin, Digoxin, Atropine, Podophyllotoxin, Caffeine, Taxol, Vincristine and Vinblastine

UNIT -05

  • Basics of Phytochemistry
    Modern methods of extraction, application of latest techniques like Spectroscopy, Chromatography and electrophoresis in the isolation, purification and identification of crude drugs.