PUBLIC HEALTH PHARMACY

PATHOPHYSIOLOGY BP204T

UNIT -01

  • Basic principles of Cell injury and Adaptation: Introduction, definitions, Homeostasis, Components and Types of Feedback systems, Causes of cellular injury, Pathogenesis (Cell membrane damage, Mitochondrial damage, Ribosome damage, Nuclear damage), Morphology of cell injury – Adaptive changes (Atrophy, Hypertrophy, hyperplasia, Metaplasia, Dysplasia), Cell swelling, Intra cellular accumulation, Calcification, Enzyme leakage and Cell Death Acidosis & Alkalosis, Electrolyte imbalance. 

  • Basic mechanism involved in the process of inflammation and repair:
    Introduction, Clinical signs of inflammation, Different types of Inflammation, Mechanism of Inflammation – Alteration in vascular permeability and blood flow, migration of WBC’s, Mediators of inflammation, Basic principles of wound healing in the skin, Pathophysiology of Atherosclerosis. 

UNIT -02

  • Cardiovascular System:
    Hypertension, congestive heart failure, ischemic heart disease (angina, myocardial infarction, atherosclerosis and arteriosclerosis)

  • Respiratory system: Asthma, Chronic obstructive airways diseases. 

  •  Renal system: Acute and chronic renal failure. 

UNIT -03

  • Hematological Diseases: Iron deficiency, megaloblastic anemia (Vitamin B12 and folic acid), sickle cell anemia,
    thalassemia, hereditary acquired anemia, hemophilia. 

  • Endocrine system: Diabetes, thyroid diseases, disorders of sex hormones.

  • Nervous system: Epilepsy, Parkinson’s disease, stroke, psychiatric disorders: depression, schizophrenia and Alzheimer’s disease.

  • Gastrointestinal system: Peptic Ulcer. 

UNIT -04

  • Inflammatory bowel diseases, jaundice, hepatitis (A, B, C, D, E, F) alcoholic liver disease.

  • Disease of bones and joints: Rheumatoid arthritis, osteoporosis and gout.

  • Principles of cancer: classification, etiology and pathogenesis of cancer.  

UNIT -05

  • Infectious diseases: Meningitis, Typhoid, Leprosy, Tuberculosis, Urinary tract infections.
  • Sexually transmitted diseases: AIDS, Syphilis, Gonorrhea.