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PHARMACOLOGY II BP503T
UNIT -01
Pharmacology of drugs acting on cardio-vascular system
Introduction to hemodynamic and electrophysiology of heart Drugs used in congestive heart failure.
Anti-hypertensive drugs.
Anti-anginal drugs.
Anti-arrhythmic drugs.
Anti-hyperlipidemic drugs.
UNIT -02
Pharmacology of drugs acting on cardio vascular system
Drug used in the therapy of shock.
Hematinics, coagulants and anticoagulants.
Fibrinolytics and anti-platelet drugs.
Plasma volume expanders.
Pharmacology of drugs acting on urinary system
Diuretics.
Anti-diuretics.
UNIT -03
- Autacoids and related drugs
- Introduction to autacoids and classification of Histamine, 5-HT and their antagonists.
- Prostaglandins, Thromboxanes and Leukotrienes.
- Angiotensin, Bradykinin and Substance P.
- Non-steroidal anti-inflammatory agents. Antigout drugs, Anti rheumatic drugs.
UNIT -04
Pharmacology of drugs acting on endocrine system
Basic concepts in endocrine pharmacology.
Anterior Pituitary hormones- analogues and their inhibitors.
Thyroid hormones- analogues and their inhibitors.
Hormones regulating plasma calcium level- Parathormone, Calcitonin and Vitamin D.
Insulin, Oral Hypogl ycemic agents and glucagon. ACTH and corticosteroids.
UNIT -05
- Pharmacology of drugs acting on endocrine system
- Androgens and Anabolic steroids.
- Estrogens, progesterone and oral contraceptives.
- Drugs acting on the uterus.
- Bioassay Principles and applications of bioassay.
- Types of bioassay. Bioassay of insulin, oxytocin, vasopressin, ACTH, d-tubocurarine, digitalis, histamine and 5- HT.